Handbook of cancer vaccines

The book is laid out into four sections including a Basic Science Background, General Vaccine and Immunotherapy Strategies, Tumor Specific Vaccines Being Developed and closing with a final section on General Background of Clinical Trials and Immune Analysis. The first section provides an overview of antigen processing, tumor antigen discovery, T cell activation, and augmenting the antigen-specific immune response. Section two progresses into a discussion of the different vaccination strategies currently under development. The third section includes chapters that introduce the reader to clinical trials in various malignancies. The final section in the book includes chapters discussing important issues in clinical trial design, analysis, and the regulatory requirements for bringing candidate vaccines through clinical trials and into clinical practice and use.