Cycloaddition reactions in organic synthesis

Cycloaddition reactions in organic synthesis

by S. Kobayashi

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Cyclo additions are among the most important tools for synthesis in organic chemistry, since this type of reaction is vital to the modern synthesis of natural products and biologically effective substances; Catalysis with metals plays an increasingly important role in these reactions, often allowing several sterocenters to be selectively integrated in the subsequent target molecule. Kobayashi and Jorgensen's manual provides numerous examples of cyclopropanes, [2+2], [3+2] and [4+2] cycloadditions and 1,3-dipolar additions. A number of experimental procedures give a concrete idea of the use of metal-catalytic cyclo additions in modern synthesis.; The book is aimed at all chemists working in synthesis laboratories, whether in industry or academia, who want to effectively use cyclo additions for their reactions.

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