Mechanistic Studies of Vertebrate Hedgehog Signaling

Mechanistic Studies of Vertebrate Hedgehog Signaling

by Hanna Tukachinsky

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Metazoans use Hedgehog signaling to direct many stages of embryonic development, and deregulation of this pathway is implicated in many types of cancer. I investigated several steps of Hedgehog pathway transduction that were poorly understood in mechanistic terms.

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