Immunotherapy in asthma

"This massive reference thoroughly analyzes the mechanisms implicated in the pathophysiology of asthma, such as T helper lymphocyte subsets, various extrinsic and intrinsic factors, and IgE receptor expression - reviewing current concepts in immunotherapeutic approaches for the treatment of this and other allergic diseases." "Written by more than 80 internationally renowned pulmonary experts and allergic disease specialists, Immunotherapy in Asthma discusses the efficacy of new medications...examines the role of metachromatic cells, lymphocytes, macrophages, and other cell types present in bronchial biopsies...presents basic topics such as the functional and phenotypic properties of Th1 and Th2 cells and their role in allergic disease and the regulation of IgE-mediated inflammatory responses...addresses the deleterious effects of smoking and passive exposure to cigarette smoke in children and adults...assesses differences and similarities between "intrinsic" and antigen-induced asthma...describes the effects of immunogenic peptides on the cytokine production profile of allergen specific CD4 [superscript +] T cells...explains the different clinical aspects of allergic responses, such as bronchial hyperreactivity and eosinophilic inflammation of the airways...reviews the genetic basis of allergy, as well as risk factors for asthma...explores oral, sublingual, local nasal, and local bronchial routes for noninjective immunotherapies...evaluates various agents with modulatory effects on normal and pathogenic immune responses...focuses on strategies for the prevention of childhood asthma...and more."--BOOK JACKET.