Immunological aspects of renal disease

"Recent advances in immunology, particularly at the molecular level, have led to a much clearer understanding of autoimmunity. This book examines renal disease from an immunological perspective; it has been designed to be suitable both as an introductory overview of the area, as well as a guide to further reading. Following an introductory chapter that discusses general immunological principles of particular relevance to autoimmunity and immunological mechanisms of renal injury, each of the major forms of renal disease with a significant immunopathogenesis is considered. The immunogenetics of each condition are reviewed, followed by a discussion of immunopathology in animal models and in human disease. A section on therapeutic aspects of immunological relevance is followed by a concluding section that contains more speculative material. A final chapter summarizes the various therapeutic strategies available, with particular emphasis on current experimental and possible future approaches."--Publisher description.