Oxygen sensing

by Sukhamay Lahiri, Gregg L. Semenza

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"Oxygen Sensing examines O[subscript 2] sensing systems in bacteria and Archaea ... demonstrates interrelationships among cell proliferation, energy metabolism, oxygen homeostasis, redox states, signal transduction, and gene expression in humans and other organisms ... details the role of excitatory and inhibitory neurotransmitters in sensory signaling ... describes the effect of hypoxia on carotid body structure and function ... and considers the effect of alterations in oxygen homeostasis on the pathophysiology of cardiac ischemia, cancer, stroke, and chronic lung disease."--BOOK JACKET.

Discussion questions for Oxygen sensing

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1
How does the book shift our perspective on oxygen from a simple biological necessity to a complex, dynamic signaling molecule that drives life at a cellular level?
2
In what ways does the exploration of oxygen sensing in primitive organisms like bacteria and Archaea deepen your appreciation for the evolutionary continuity of life?
3
Semenza and Lahiri connect oxygen homeostasis to major modern pathologies like cancer, stroke, and cardiac ischemia; how does this interdisciplinary approach change the way you view the relationship between basic science and clinical medicine?

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