Control of biofilm infections by signal manipulation

"The medical miracle of antibiotics is being eroded by the emergence and spread of bacterial drug resistance. This is compounded by the fact that bacterial bio-films are believed to be a common cause of persistent infections, where growing in a biofilm, bacteria are protected from the host's immune response and antibiotics. This book describes the molecular mechanisms of bacterial cell-to-cell communication (quorum sensing), the development of anti-biofilm inhibitors, and the use of such inhibitors to prevent and treat biofilm-associated bacterial infections in animals and humans."--Jacket.