Design and analysis of non-inferiority trials

Design and analysis of non-inferiority trials

by Mark Rothmann, Ivan Chan, Mark D. Rothmann, Brian Wiens

Part of Chapman & Hall/CRC biostatistics series

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"The increased use of non-inferiority analysis has been accompanied by a proliferation of research on the design and analysis of non-inferiority studies. Design and Analysis of Non-Inferiority Trials brings together this body of research and confronts the issues involved in the design of a non-inferiority trial. Using examples from real clinical trials, the book discusses general and regulatory issues and illustrates how they affect analysis. Each chapter begins with a non-technical introduction, so the subject is easily understood by those without prior knowledge of non-inferiority clinical trials. The book also provides detailed mathematical approaches along with their mathematical properties"--Provided by publisher.

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