Homology Folding of Proteins

Homology Folding of Proteins

by Subhashini Srinivasan

Part of Biotechnology intelligence unit

1997
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About
The homology modeling method is an important tool in protein engineering and drug design when an experimental 3D structure is not available. Development of distance geometry-based homology modeling, offers a holistic approach to protein modeling thus expanding the scope of this method to protein threading and protein folding. This book is the first of its kind to give a complete account of the field, including structural principles and sequence-to-structural relationships in the PDB. This book is intended for use by biologists and modelers who are new to homology modeling methods, and serves as a good starting point for further research.

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