Transcription of ribosomal RNA genes by eukaryotic RNA polymerase I

Transcription of ribosomal RNA genes by eukaryotic RNA polymerase I

by Marvin R. Paule

Part of Biotechnology intelligence unit

1998

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About
The mechanism by which ribosomal RNA is synthesized has been a topic of intensive research for nearly 30 years. However, in 1981 the first in vitro transcription system for ribosomal RNA from a eukaryote, mouse ascites cells, was reported, followed rapidly by similar systems in a variety of other eukaryotes, which were revealed by a relatively small number of research groups. This monograph is the first to bring together the results and opinions of all these groups.

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