Life from an RNA world

Life from an RNA world

by Michael Yarus

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A majority of evolutionary biologists believe that we now can envision our biological predecessors--not the first, but nearly the first, living beings on Earth. This book is about these vanished forebears. The era between the first rudimentary life on Earth and the appearance of more complex beings is called the RNA world. It is RNA (ribonucleic acid) long believed to be a mere biologic copier and messenger, that offers a glimpse into our ancient predecessors. To describe early RNA creatures, here called "ribocytes" or RNA cells, the author uses basics of molecular biology. He reviews our current understanding of the tree of life, examines the structure of RNA itself, explains the operation of the genetic code, and more. Courting controversy among those who question the role of ribocytes -- citing the chemical fragility of RNA and the uncertainty about the origin of an RNA synthetic apparatus -- he offers a vision of early life on Earth.

Discussion questions for Life from an RNA world

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  1. 1

    The book describes the "RNA world" as a crucial era between rudimentary life and more complex beings. What were your own preconceptions about the earliest forms of life on Earth before reading, and how did Yarus's vision of "ribocytes" challenge or confirm them?

  2. 2

    Yarus uses the basics of molecular biology to describe these ancient RNA creatures. Did this approach make the scientific concepts more accessible or more daunting for you, and how did it affect your ability to "envision" these vanished forebears?

  3. 3

    The author acknowledges the controversy surrounding the RNA world hypothesis, particularly concerning RNA's chemical fragility and the uncertainty about the origin of a synthetic apparatus. How effectively do you feel Yarus addresses these criticisms, and did his arguments sway your opinion?

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